Increase of PlGF (Placental Growth Factor) Level After Administration of Dydrogesterone in Pregnancy

Placental Growth Factor (PlGF) in first trimester of pregnancy

Placental Growth Factor (PlGF) in first trimester of pregnancy

Placental Growth Factor (PLGF) in the first trimester of pregnancy –Pre-eclampsia, SGA and trisomies

Placental growth factor (PlGF)-specific uptake in tumor microenvironment of 89Zr-labeled PlGF antibody RO5323441.

UNLABELLED Placental growth factor (PlGF) is a member of the proangiogenic vascular endothelial growth factor family, which is upregulated in many tumors. RO5323441, a humanized monoclonal antibody against PlGF, showed antitumor activity in human tumor xenografts. We therefore aimed to radiolabel RO5323441 and preclinically validate this tracer to study drug tumor uptake and organ distribution ...

Placental Growth Factor Administration Abolishes Placental Ischemia-Induced Hypertension.

Preeclampsia is a pregnancy-specific disorder of new-onset hypertension. Unfortunately, the most effective treatment is early delivery of the fetus and placenta. Placental ischemia appears central to the pathogenesis of preeclampsia because placental ischemia/hypoxia induced in animals by reduced uterine perfusion pressure (RUPP) or in humans stimulates release of hypertensive placental factors...